Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJMBR (3) Autor Zhang,F. (3) Bao,Z.J. (1) Chen,D. (1) Dai,F. (1) Dong,S.W. (1) Huang,Y.Q. (1) Lei,M. (1) Lü,Q. (1) Shi,D.M. (1) Sun,D. (1) Tang,L. (1) Tong,N. (1) Xiang,P. (1) Xiao,L. (1) Xu,J.Z. (1) Yang,C. (1) Yin,S.M. (1) Zhang,G.S. (1) Zhang,Y. (1) Zhang,Z.H. (1) Mais... Palavra-chave Bone tissue engineering (1) CTLA4 (1) Efficacy (1) Eradication (1) Gastrectomy (1) Gastric stump (1) Gitelman syndrome (1) Helicobacter pylori (1) Homozygous mutant (1) Immunomodulatory (1) Mesenchymal stem cells (1) Pedigree (1) SLC12A3 gene (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2016 (2) 2015 (1) País Brazil (3) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última A novel homozygous mutation in the solute carrier family 12 member 3 gene in a Chinese family with Gitelman syndrome BJMBR Zhang,Y.; Zhang,F.; Chen,D.; Lü,Q.; Tang,L.; Yang,C.; Lei,M.; Tong,N.. Loss of function of mutated solute carrier family 12 member 3 (SLC12A3) gene is the most frequent etiology for Gitelman syndrome (GS), which is mainly manifested by hypokalemia, hypomagnesemia and hypocalciuria. We report the genetic characteristics of one suspicious Chinese GS pedigree by gene sequencing. Complete sequencing analysis of the SLC12A3 gene revealed that both the proband and his elder sister had a novel homozygous SLC12A3 mutation: c.2099T>C and p.Leu700Pro. Moreover, the SLC12A3 genes of his mother and daughter encoded the same mutated heterozygote. It was noted that in this pedigree, only the proband complained about recurrent episodes of bilateral lower limb weakness over 8 years, while his elder sister, mother and daughter did not... Tipo: Info:eu-repo/semantics/article Palavras-chave: Gitelman syndrome; SLC12A3 gene; Homozygous mutant; Pedigree. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001100701 CTLA4 enhances the osteogenic differentiation of allogeneic human mesenchymal stem cells in a model of immune activation BJMBR Dai,F.; Zhang,F.; Sun,D.; Zhang,Z.H.; Dong,S.W.; Xu,J.Z.. Allogeneic mesenchymal stem cells (allo-MSCs) have recently garnered increasing interest for their broad clinical therapy applications. Despite this, many studies have shown that allo-MSCs are associated with a high rate of graft rejection unless immunosuppressive therapy is administered to control allo-immune responses. Cytotoxic T-lymphocyte-associated protein 4 (CTLA4) is a co-inhibitory molecule expressed on T cells that mediates the inhibition of T-cell function. Here, we investigated the osteogenic differentiation potency of allo-MSCs in an activated immune system that mimics the in vivo allo-MSC grafting microenvironment and explored the immunomodulatory role of the helper T cell receptor CTLA4 in this process. We found that MSC osteogenic... Tipo: Info:eu-repo/semantics/article Palavras-chave: CTLA4; Mesenchymal stem cells; Immunomodulatory; Bone tissue engineering. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000700629 Efficacy of a quadruple therapy regimen for Helicobacter pylori eradication after partial gastrectomy BJMBR Zhang,F.; Bao,Z.J.; Shi,D.M.; Xiang,P.; Xiao,L.; Huang,Y.Q.; Zhang,G.S.; Yin,S.M.. We aimed to evaluate the effectiveness and safety of bismuth-containing quadruple therapy plus postural change after dosing for Helicobacter pylori eradication in gastrectomized patients. We compared 76 gastric stump patients with H. pylori infection (GS group) with 50 non-gastrectomized H. pylori-positive patients who met the treatment indication (controls). The GS group was divided into GS group 1 and GS group 2. All groups were administered bismuth potassium citrate (220 mg), esomeprazole (20 mg), amoxicillin (1.0 g), and furazolidone (100 mg) twice daily for 14 days. GS group 1 maintained a left lateral horizontal position for 30 min after dosing. H. pylori was detected using rapid urease testing and histologic examination of gastric mucosa before and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Helicobacter pylori; Gastrectomy; Gastric stump; Eradication; Efficacy. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200702 Registros recuperados: 3 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco